A Simple Method for the Prediction of Therapeutic Proteins (Monoclonal and Polyclonal Antibodies and Non-Antibody Proteins) for First-in-Pediatric Dose Selection: Application of Salisbury Rule
In order to conduct a pediatric clinical trial, it is important to optimize pediatric dose as accurately as possible. In this study, a simple weight-based method known as ‘Salisbury Rule’ was used to predict pediatric dose for therapeutic proteins and was then compared with the observed pediatric do...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-10-01
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| Series: | Antibodies |
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| Online Access: | https://www.mdpi.com/2073-4468/11/4/66 |