Astrocyte activation in the anterior cingulate cortex and altered glutamatergic gene expression during paclitaxel-induced neuropathic pain in mice

Spinal astrocyte activation contributes to the pathogenesis of paclitaxel-induced neuropathic pain (PINP) in animal models. We examined glial fibrillary acidic protein (GFAP; an astrocyte marker) immunoreactivity and gene expression of GFAP, glutamate transporters and receptor subunits by real time...

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Bibliographic Details
Main Author: Willias Masocha
Format: Article
Language:English
Published: PeerJ Inc. 2015-10-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/1350.pdf