Structural determinants for subnanomolar inhibition of the secreted aspartic protease Sapp1p from Candida parapsilosis
Pathogenic Candida albicans yeasts frequently cause infections in hospitals. Antifungal drugs lose effectiveness due to other Candida species and resistance. New medications are thus required. Secreted aspartic protease of C. parapsilosis (Sapp1p) is a promising target. We have thus solved the cryst...
| Những tác giả chính: | , , , , , , |
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| Định dạng: | Bài viết |
| Ngôn ngữ: | English |
| Được phát hành: |
Taylor & Francis Group
2021-01-01
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| Loạt: | Journal of Enzyme Inhibition and Medicinal Chemistry |
| Những chủ đề: | |
| Truy cập trực tuyến: | http://dx.doi.org/10.1080/14756366.2021.1906664 |