Lgr5 Methylation in Cancer Stem Cell Differentiation and Prognosis-Prediction in Colorectal Cancer.

Lgr5 Methylation in Cancer Stem Cell Differentiation and Prognosis-Prediction in Colorectal Cancer.

Leucine-rich-repeat-containing G-protein-coupled receptor 5 (lgr5) is a candidate marker for colorectal cancer stem cells (CSC). In the current study, we investigated the methylation status within thelgr5 promoter and evaluated its relationship with CSC differentiation, prognosis for colorectal canc...

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Bibliographic Details
Main Authors: Shasha Su, Feng Hong, Yanling Liang, Jieqiong Zhou, Yan Liang, Kequan Chen, Xinying Wang, Zhongqiu Wang, Zhiqing Wang, Cassie Chang, Weihua Han, Wei Gong, Haitao Qin, Bo Jiang, Huabao Xiong, Liang Peng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4657969?pdf=render

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http://europepmc.org/articles/PMC4657969?pdf=render

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