SARS-CoV-2 Spike Protein and Its Receptor Binding Domain Promote a Proinflammatory Activation Profile on Human Dendritic Cells

SARS-CoV-2 Spike Protein and Its Receptor Binding Domain Promote a Proinflammatory Activation Profile on Human Dendritic Cells

Dendritic cells (DCs) are the most potent antigen-presenting cells, and their function is essential to configure adaptative immunity and avoid excessive inflammation. DCs are predicted to play a crucial role in the clinical evolution of the infection by the severe acute respiratory syndrome (SARS) c...

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Bibliographic Details
Main Authors: Dante Barreda, César Santiago, Juan R. Rodríguez, José F. Rodríguez, José M. Casasnovas, Isabel Mérida, Antonia Ávila-Flores
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cells
Subjects:
COVID-19
ACE-2
inflammation
cytokines
Online Access:https://www.mdpi.com/2073-4409/10/12/3279

Internet

https://www.mdpi.com/2073-4409/10/12/3279

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