SARS-CoV-2 Spike Protein and Its Receptor Binding Domain Promote a Proinflammatory Activation Profile on Human Dendritic Cells
Dendritic cells (DCs) are the most potent antigen-presenting cells, and their function is essential to configure adaptative immunity and avoid excessive inflammation. DCs are predicted to play a crucial role in the clinical evolution of the infection by the severe acute respiratory syndrome (SARS) c...
Main Authors: | Dante Barreda, César Santiago, Juan R. Rodríguez, José F. Rodríguez, José M. Casasnovas, Isabel Mérida, Antonia Ávila-Flores |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-11-01
|
Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/10/12/3279 |
Similar Items
-
Regulation of Proinflammatory Molecules and Tissue Factor by SARS-CoV-2 Spike Protein in Human Placental Cells: Implications for SARS-CoV-2 Pathogenesis in Pregnant Women
by: Xiaofang Guo, et al.
Published: (2022-04-01) -
Role of SARS-CoV-2 Spike-Protein-Induced Activation of Microglia and Mast Cells in the Pathogenesis of Neuro-COVID
by: Theoharis C. Theoharides, et al.
Published: (2023-02-01) -
Computational Analysis of Mutations in the Receptor-Binding Domain of SARS-CoV-2 Spike and Their Effects on Antibody Binding
by: Marine E. Bozdaganyan, et al.
Published: (2022-01-01) -
Assessment of the binding interactions of SARS-CoV-2 spike glycoprotein variants
by: Deepa Raghu, et al.
Published: (2022-02-01) -
The Recognition Pathway of the SARS-CoV-2 Spike Receptor-Binding Domain to Human Angiotensin-Converting Enzyme 2
by: Can Peng, et al.
Published: (2024-04-01)