Instantaneous antidepressant effect of lateral habenula deep brain stimulation in rats studied with functional MRI

Instantaneous antidepressant effect of lateral habenula deep brain stimulation in rats studied with functional MRI

The available treatments for depression have substantial limitations, including low response rates and substantial lag time before a response is achieved. We applied deep brain stimulation (DBS) to the lateral habenula (LHb) of two rat models of depression (Wistar Kyoto rats and lipopolysaccharide-t...

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Bibliographic Details
Main Authors: Gen Li, Binshi Bo, Puxin Wang, Peixing Qian, Mingzhe Li, Yuyan Li, Chuanjun Tong, Kaiwei Zhang, Baogui Zhang, Tianzi Jiang, Zhifeng Liang, Xiaojie Duan
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-06-01
Series:eLife
Subjects:
treatment-resistant depression
brain modulation
fast-acting antidepressant
brain activity mapping
Online Access:https://elifesciences.org/articles/84693

Internet

https://elifesciences.org/articles/84693

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