Chromosomal Aberration t(14;17)(q32;q21) Simultaneously Activates HOXB5 and miR10a in Triple-Hit B-Cell Lymphoma

Chromosomal Aberration t(14;17)(q32;q21) Simultaneously Activates HOXB5 and miR10a in Triple-Hit B-Cell Lymphoma

<i>BCL2</i>, <i>BCL6</i> and <i>MYC</i> are major oncogenes in B-cell lymphoma. Their aberrant activation frequently occurs via chromosomal translocations which juxtapose light or heavy chain immunoglobulin (IG) genes to <i>BCL2</i> and <i>MYC<...

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Bibliographic Details
Main Authors: Stefan Nagel, Claudia Pommerenke, Corinna Meyer, Maren Kaufmann, Roderick A. F. MacLeod
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Biomedicines
Subjects:
Hodgkin lymphoma
homeodomain
HOX
KCNJ12
miR17
miR196a
Online Access:https://www.mdpi.com/2227-9059/11/6/1758

Internet

https://www.mdpi.com/2227-9059/11/6/1758

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