Association of a novel point mutation in MSH2 gene with familial multiple primary cancers

Association of a novel point mutation in MSH2 gene with familial multiple primary cancers

Abstract Background Multiple primary cancers (MPC) have been identified as two or more cancers without any subordinate relationship that occur either simultaneously or metachronously in the same or different organs of an individual. Lynch syndrome is an autosomal dominant genetic disorder that incre...

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Bibliographic Details
Main Authors: Hai Hu, Hong Li, Feng Jiao, Ting Han, Meng Zhuo, Jiujie Cui, Yixue Li, Liwei Wang
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Journal of Hematology & Oncology
Subjects:
Lynch syndrome
Cancer landscape
MSH2
Carcinogenesis
Multiple primary cancers
Online Access:http://link.springer.com/article/10.1186/s13045-017-0523-y

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http://link.springer.com/article/10.1186/s13045-017-0523-y

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