Agonist antagonist interactions at the rapidly desensitizing P2X3 receptor.

P2X3 receptors (P2XRs), as members of the purine receptor family, are deeply involved in chronic pain sensation and therefore, specific, competitive antagonists are of great interest for perspective pain management. Heretofore, Schild plot analysis has been commonly used for studying the interaction...

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Bibliographic Details
Main Authors: Nick Helms, Maria Kowalski, Peter Illes, Thomas Riedel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3815160?pdf=render