Interleukin-34 restores blood-brain barrier integrity by upregulating tight junction proteins in endothelial cells.

Interleukin-34 restores blood-brain barrier integrity by upregulating tight junction proteins in endothelial cells.

Interleukin-34 (IL-34) is a newly discovered cytokine as an additional ligand for colony stimulating factor-1 receptor (CSF1R), and its functions are expected to overlap with colony stimulating factor-1/macrophage-colony stimulating factor. We have previously shown that the IL-34 is primarily produc...

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Bibliographic Details
Main Authors: Shijie Jin, Yoshifumi Sonobe, Jun Kawanokuchi, Hiroshi Horiuchi, Yi Cheng, Yue Wang, Tetsuya Mizuno, Hideyuki Takeuchi, Akio Suzumura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4275171?pdf=render

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http://europepmc.org/articles/PMC4275171?pdf=render

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