Recovery of recombinant Mycobacterium tuberculosis antigens fused with cell wall-anchoring motif (LysM) from inclusion bodies using non-denaturing reagent (N-laurylsarcosine)

Recovery of recombinant Mycobacterium tuberculosis antigens fused with cell wall-anchoring motif (LysM) from inclusion bodies using non-denaturing reagent (N-laurylsarcosine)

Abstract Background The current limitations of conventional BCG vaccines highlights the importance in developing novel and effective vaccines against tuberculosis (TB). The utilization of probiotics such as Lactobacillus plantarum for the delivery of TB antigens through in-trans surface display prov...

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Bibliographic Details
Main Authors: Anhar Danial Mustafa, Jeevanathan Kalyanasundram, Sarah Sabidi, Adelene Ai-Lian Song, Maha Abdullah, Raha Abdul Rahim, Khatijah Yusoff
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Biotechnology
Subjects:
Mycobacterium tuberculosis antigen
Lysine motif
Overexpression
Inclusion body
TB subunit vaccine
N-lauroylsarcosine
Online Access:http://link.springer.com/article/10.1186/s12896-019-0522-x

Internet

http://link.springer.com/article/10.1186/s12896-019-0522-x

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