Granzyme B mediates impaired healing of pressure injuries in aged skin

Granzyme B mediates impaired healing of pressure injuries in aged skin

Abstract Pressure injuries (PIs), also known as bedsores or pressure ulcers, are a major cause of death and morbidity in the elderly. The serine protease, Granzyme B (GzmB), contributes to skin aging and impaired wound healing. Aging is a major risk factor for PIs; thus, the role of GzmB in PI patho...

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Bibliographic Details
Main Authors: Christopher T. Turner, Juliana Bolsoni, Matthew R. Zeglinski, Hongyan Zhao, Tatjana Ponomarev, Katlyn Richardson, Sho Hiroyasu, Erin Schmid, Anthony Papp, David J. Granville
Format: Article
Language:English
Published: Nature Portfolio 2021-03-01
Series:npj Aging and Mechanisms of Disease
Online Access:https://doi.org/10.1038/s41514-021-00059-6

Internet

https://doi.org/10.1038/s41514-021-00059-6

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