Human Beta Defensin 2 Ameliorated Alcohol-Associated Liver Disease in Mice

Human Beta Defensin 2 Ameliorated Alcohol-Associated Liver Disease in Mice

Alcohol-associated liver disease (ALD) is a prevalent liver disorder and significant global healthcare burden with limited effective therapeutic options. The gut-liver axis is a critical factor contributing to susceptibility to liver injury due to alcohol consumption. In the current study, we tested...

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Bibliographic Details
Main Authors: Jeffrey B. Warner, Ida S. Larsen, Josiah E. Hardesty, Ying L. Song, Dennis R. Warner, Craig J. McClain, Rui Sun, Zhongbin Deng, Benjamin A. H. Jensen, Irina A. Kirpich
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Physiology
Subjects:
alcohol
defensin
gut-liver axis
intestine
ALD
immunomodulation
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.812882/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.812882/full

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