Genetically Encoded Ratiometric pH Sensors for the Measurement of Intra- and Extracellular pH and Internalization Rates

Genetically Encoded Ratiometric pH Sensors for the Measurement of Intra- and Extracellular pH and Internalization Rates

pH-sensitive fluorescent proteins as genetically encoded pH sensors are promising tools for monitoring intra- and extracellular pH. However, there is a lack of ratiometric pH sensors, which offer a good dynamic range and can be purified and applied extracellularly to investigate uptake. In our study...

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Bibliographic Details
Main Authors: Lennard Karsten, Lukas Goett-Zink, Julian Schmitz, Raimund Hoffrogge, Alexander Grünberger, Tilman Kottke, Kristian M. Müller
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Biosensors
Subjects:
pH sensor
EGF
ratiometric
GFP
FRET
dynamic range
Online Access:https://www.mdpi.com/2079-6374/12/5/271

Internet

https://www.mdpi.com/2079-6374/12/5/271

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