Genetically Encoded Ratiometric pH Sensors for the Measurement of Intra- and Extracellular pH and Internalization Rates
pH-sensitive fluorescent proteins as genetically encoded pH sensors are promising tools for monitoring intra- and extracellular pH. However, there is a lack of ratiometric pH sensors, which offer a good dynamic range and can be purified and applied extracellularly to investigate uptake. In our study...
Main Authors: | Lennard Karsten, Lukas Goett-Zink, Julian Schmitz, Raimund Hoffrogge, Alexander Grünberger, Tilman Kottke, Kristian M. Müller |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-04-01
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Series: | Biosensors |
Subjects: | |
Online Access: | https://www.mdpi.com/2079-6374/12/5/271 |
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