Low-dose targeted radionuclide therapy synergizes with CAR T cells and enhances tumor response

Ionizing radiation has garnered considerable attention as a combination partner for immunotherapy due to its potential immunostimulatory effects. In contrast to the more commonly used external beam radiation, we explored the feasibility of combining chimeric antigen receptor (CAR) T cell therapy wit...

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Bibliographic Details
Main Authors: Yanping Yang, Yogindra Vedvyas, Yago Alcaina, Ju Y. Son, Irene M. Min, Moonsoo M. Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1355388/full