Frontline Blinatumomab in Older Adults with Philadelphia Chromosome-Negative B-Cell Acute Lymphoblastic Leukemia

Outcomes of acute lymphoblastic leukemia (ALL) in older adults treated with chemotherapy are poor. The CD19/CD3 bispecific T-cell engager (BiTE) antibody blinatumomab is approved for refractory, relapsed or minimal/measurable residual disease (MRD)-positive B-cell ALL, but there is little experience...

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Bibliographic Details
Main Authors: Sandrine Niyongere, Gabriela Sanchez-Petitto, Jack Masur, Maria R. Baer, Vu H. Duong, Ashkan Emadi
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/13/6/124