Thioredoxin 2 protects mice against experimental myocardial infarction

Thioredoxin 2 protects mice against experimental myocardial infarction

Experimental Myocardial infarction (MI) using ligation procedure induces cardiac dysfunction, high level of ROS, inflammation, apoptosis, fibrosis and cardiomyocyte (CM) loss. AAV overexpressing human Trx-2, specifically in CM mitochondria improves mouse cardiac function, reduces the size of cardiac...

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Bibliographic Details
Main Authors: Tania Medali, Dominique Couchie, Nathalie Mougenot, Maria Mihoc, Olaf Bergmann, Wouter Derks, Celio X Santos, Bertrand Friguet, Mustapha Rouis
Format: Article
Language:English
Published: Bioscientifica 2024-04-01
Series:Redox Experimental Medicine
Subjects:
myocardial infarction
heart failure
thioredoxin 2
Online Access:https://rem.bioscientifica.com/view/journals/rem/2024/1/REM-23-0029.xml

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https://rem.bioscientifica.com/view/journals/rem/2024/1/REM-23-0029.xml

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