Molecular Mechanisms of Obesity-Linked Cardiac Dysfunction: An Up-Date on Current Knowledge

Molecular Mechanisms of Obesity-Linked Cardiac Dysfunction: An Up-Date on Current Knowledge

Obesity is defined as excessive body fat accumulation, and worldwide obesity has nearly tripled since 1975. Excess of free fatty acids (FFAs) and triglycerides in obese individuals promote ectopic lipid accumulation in the liver, skeletal muscle tissue, and heart, among others, inducing insulin resi...

Full description

Bibliographic Details
Main Authors: Jorge Gutiérrez-Cuevas, Ana Sandoval-Rodriguez, Alejandra Meza-Rios, Hugo Christian Monroy-Ramírez, Marina Galicia-Moreno, Jesús García-Bañuelos, Arturo Santos, Juan Armendariz-Borunda
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cells
Subjects:
obesity
cardiovascular diseases
pathophysiology
PPARs
epigenetic modifications
gut microbiota dysbiosis
Online Access:https://www.mdpi.com/2073-4409/10/3/629

Internet

https://www.mdpi.com/2073-4409/10/3/629

Similar Items