Fibrin(ogen) engagement of S. aureus promotes the host antimicrobial response and suppression of microbe dissemination following peritoneal infection.

Fibrin(ogen) engagement of S. aureus promotes the host antimicrobial response and suppression of microbe dissemination following peritoneal infection.

The blood-clotting protein fibrin(ogen) plays a critical role in host defense against invading pathogens, particularly against peritoneal infection by the Gram-positive microbe Staphylococcus aureus. Here, we tested the hypothesis that direct binding between fibrin(ogen) and S. aureus is a component...

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Bibliographic Details
Main Authors: Oscar Negrón, Woosuk S Hur, Joni Prasad, David S Paul, Sarah E Rowe, Jay L Degen, Sara R Abrahams, Silvio Antoniak, Brian P Conlon, Wolfgang Bergmeier, Magnus Hӧӧk, Matthew J Flick
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1010227

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https://doi.org/10.1371/journal.ppat.1010227

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