Pontin is essential for murine hematopoietic stem cell survival
Pontin is a highly conserved DNA helicase/ATPase which is a component of several macromolecular complexes with functions that include DNA repair, telomere maintenance and tumor suppression. While Pontin is known to be essential in yeast, fruit flies and frogs, its physiological role in mammalian org...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Ferrata Storti Foundation
2012-09-01
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Series: | Haematologica |
Online Access: | https://haematologica.org/article/view/6397 |