Pontin is essential for murine hematopoietic stem cell survival

Pontin is a highly conserved DNA helicase/ATPase which is a component of several macromolecular complexes with functions that include DNA repair, telomere maintenance and tumor suppression. While Pontin is known to be essential in yeast, fruit flies and frogs, its physiological role in mammalian org...

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Bibliographic Details
Main Authors: Oxana Bereshchenko, Elena Mancini, Luisa Luciani, Adriana Gambardella, Carlo Riccardi, Claus Nerlov
Format: Article
Language:English
Published: Ferrata Storti Foundation 2012-09-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/6397