Profile of Histone H3 Lysine 4 Trimethylation and the Effect of Lipopolysaccharide/Immune Complex-Activated Macrophages on Endotoxemia

Profile of Histone H3 Lysine 4 Trimethylation and the Effect of Lipopolysaccharide/Immune Complex-Activated Macrophages on Endotoxemia

Macrophage plasticity is a process that allows macrophages to switch between two opposing phenotypes based on differential stimuli. Interferon γ (IFNγ)-primed macrophages stimulated with lipopolysaccharide (LPS) [M(IFNγ+LPS)] produce high levels of pro-inflammatory cytokines such as IL-12, TNFα, and...

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Bibliographic Details
Main Authors: Vichaya Ruenjaiman, Patcharavadee Butta, Yu-Wei Leu, Monnat Pongpanich, Asada Leelahavanichkul, Patipark Kueanjinda, Tanapat Palaga
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Immunology
Subjects:
macrophage
LPS
immune complex
epigenetics
H3K4me3
endotoxemia
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02956/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02956/full

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