Reduced bonobo MHC class I diversity predicts a reduced viral peptide binding ability compared to chimpanzees

Reduced bonobo MHC class I diversity predicts a reduced viral peptide binding ability compared to chimpanzees

Abstract Background The highly polymorphic genes of the major histocompatibility complex (MHC) class I are involved in defense against viruses and other intracellular pathogens. Although several studies found reduced MHC class I diversity in bonobos in comparison to the closely related chimpanzee, i...

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Bibliographic Details
Main Authors: Vincent Maibach, Linda Vigilant
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Evolutionary Biology
Subjects:
Pan paniscus
Pan troglodytes
Great apes
NetMHCpan
Major histocompatibility complex
Online Access:http://link.springer.com/article/10.1186/s12862-019-1352-0

Internet

http://link.springer.com/article/10.1186/s12862-019-1352-0

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