Popeye domain containing proteins modulate the voltage-gated cardiac sodium channel Nav1.5

Popeye domain containing proteins modulate the voltage-gated cardiac sodium channel Nav1.5

Summary: Popeye domain containing (POPDC) proteins are predominantly expressed in the heart and skeletal muscle, modulating the K2P potassium channel TREK-1 in a cAMP-dependent manner. POPDC1 and POPDC2 variants cause cardiac conduction disorders with or without muscular dystrophy. Searching for POP...

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Bibliographic Details
Main Authors: Susanne Rinné, Aytug K. Kiper, Ralf Jacob, Beatriz Ortiz-Bonnin, Roland F.R. Schindler, Sabine Fischer, Marlene Komadowski, Emilia De Martino, Martin K.-H. Schäfer, Tamina Cornelius, Larissa Fabritz, Christian S.M. Helker, Thomas Brand, Niels Decher
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:iScience
Subjects:
Biochemistry
Molecular biology
Physiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224009180

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http://www.sciencedirect.com/science/article/pii/S2589004224009180

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