ELK3-CXCL16 axis determines natural killer cell cytotoxicity via the chemotactic activity of CXCL16 in triple negative breast cancer

ELK3-CXCL16 axis determines natural killer cell cytotoxicity via the chemotactic activity of CXCL16 in triple negative breast cancer

Triple-negative breast cancer (TNBC) is the most challenging subtype of breast cancer because of its aggressive behavior and the limited therapeutic strategies available. In the last decade, immunotherapy has become a promising treatment to prolong survival in advanced solid cancers including TNBC....

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Bibliographic Details
Main Authors: Hae-Yun Jung, Dae-Keum Lee, Minwook Lee, Seung Hee Choi, Joo Dong Park, Eun-Su Ko, Jongwon Lee, Kyung-Soon Park
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:OncoImmunology
Subjects:
CXCL16
ELK3
immunosuppressive tumor microenvironment
NK cell cytotoxicity
NK cell recruitment
triple-negative breast cancer
Online Access:https://www.tandfonline.com/doi/10.1080/2162402X.2023.2190671

Internet

https://www.tandfonline.com/doi/10.1080/2162402X.2023.2190671

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