Pro-angiogenic New Chloro-Azaphilone Derivatives From the Hadal Trench-Derived Fungus Chaetomium globosum YP-106

Pro-angiogenic New Chloro-Azaphilone Derivatives From the Hadal Trench-Derived Fungus Chaetomium globosum YP-106

Five new chloro-azaphilones, chaetofanixins A–E (1–5), and five known analogs (6–10) were isolated and identified from the hadal trench-derived fungus Chaetomium globosum YP-106. The structure of chaetofanixin E (5) is unique and interesting, bearing a highly rigid 6/6/5/3/5 penta-cyclic ring system...

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Bibliographic Details
Main Authors: Yaqin Fan, Chunjiao Jiang, Yan Zhang, Zhiheng Ma, Peihai Li, Lizhong Guo, Ting Feng, Liman Zhou, Lili Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Microbiology
Subjects:
hadal trench-derived fungus
metabolites
chloro-azaphilones
pro-angiogenic activity
Chaetomium globosum
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.943452/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.943452/full

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