Autoimmune and neuropsychiatric phenotypes in a Mecp2 transgenic mouse model on C57BL/6 background

Autoimmune and neuropsychiatric phenotypes in a Mecp2 transgenic mouse model on C57BL/6 background

IntroductionSystemic Lupus Erythematosus (SLE) impacts the central nervous system (CNS), leading to severe neurological and psychiatric manifestations known as neuropsychiatric lupus (NPSLE). The complexity and heterogeneity of clinical presentations of NPSLE impede direct investigation of disease e...

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Bibliographic Details
Main Authors: Yaxi Li, Shu Zhang, Chenling Tang, Bowen Yang, Fatin Atrooz, Zhifeng Ren, Chandra Mohan, Samina Salim, Tianfu Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Immunology
Subjects:
NPSLE
mouse model
MeCP2
autoantigen array
immune phenotypes
behavior tests
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1370254/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1370254/full

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