HIPPO: HIstogram-based Pseudo-POtential for scoring protein-ssRNA fragment-based docking poses

HIPPO: HIstogram-based Pseudo-POtential for scoring protein-ssRNA fragment-based docking poses

Abstract Background The RNA-Recognition motif (RRM) is a protein domain that binds single-stranded RNA (ssRNA) and is present in as much as 2% of the human genome. Despite this important role in biology, RRM-ssRNA interactions are very challenging to study on the structural level because of the rema...

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Bibliographic Details
Main Authors: Anna Kravchenko, Sjoerd Jacob de Vries, Malika Smaïl-Tabbone, Isaure Chauvot de Beauchene
Format: Article
Language:English
Published: BMC 2024-03-01
Series:BMC Bioinformatics
Subjects:
Scoring function
Protein-ssRNA docking
RRM-ssRNA docking
Fragment-based docking
Online Access:https://doi.org/10.1186/s12859-024-05733-6

Internet

https://doi.org/10.1186/s12859-024-05733-6

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