NUP98 Rearrangements in AML: Molecular Mechanisms and Clinical Implications

NUP98 Rearrangements in AML: Molecular Mechanisms and Clinical Implications

<i>NUP98</i> fusions constitute a small subgroup of AML patients and remain a high-risk AML subtype. There are approximately 30 types of <i>NUP98</i> fusions identified in AML patients. These patients show resistance to currently available therapies and poor clinical outcomes...

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Bibliographic Details
Main Author: Sagarajit Mohanty
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Onco
Subjects:
leukemia
AML
translocations
fusion genes
<i>NUP98</i> fusions
<i>NUP98::NSD1</i>
Online Access:https://www.mdpi.com/2673-7523/3/3/11

Internet

https://www.mdpi.com/2673-7523/3/3/11

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