Liraglutide abrogates nephrotoxic effects of chemotherapies

Liraglutide abrogates nephrotoxic effects of chemotherapies

Acute kidney injury (AKI) is a common clinical complication. Cisplatin (Cis) is an effective chemotherapeutic drug; however, its acute nephrotoxicity often limits its application. The role of liraglutide (Lir), an agonist of the glucagon-like peptide-1 receptor (GLP-1R), has recently attracted incre...

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Bibliographic Details
Main Authors: Cong Xu, Chenqi Lu, Zhimin Wang, Xiaofan Hu, Shanglin Li, Yanan Xie, Yang Qiu, Rui Cao, Yakun Li, Jun Yang
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Pharmacological Research
Subjects:
Acute kidney injury
Cisplatin
Liraglutide
GLP-1R
Metabolite
HMGB1
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661823000361

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http://www.sciencedirect.com/science/article/pii/S1043661823000361

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