Systemic administration of clinical-grade multilineage-differentiating stress-enduring cells ameliorates hypoxic–ischemic brain injury in neonatal rats

Systemic administration of clinical-grade multilineage-differentiating stress-enduring cells ameliorates hypoxic–ischemic brain injury in neonatal rats

Abstract Multilineage-differentiating stress-enduring (Muse) cells are endogenous reparative pluripotent stem cells present in the bone marrow, peripheral blood, and organ connective tissues. We assessed the homing and therapeutic effects of systemically administered nafimestrocel, a clinical-grade...

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Bibliographic Details
Main Authors: Kazuto Ueda, Yoshiaki Sato, Shinobu Shimizu, Toshihiko Suzuki, Atsuto Onoda, Ryosuke Miura, Shoji Go, Haruka Mimatsu, Yuma Kitase, Yuta Yamashita, Keiichi Irie, Masahiro Tsuji, Kenichi Mishima, Masaaki Mizuno, Yoshiyuki Takahashi, Mari Dezawa, Masahiro Hayakawa
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-41026-3

Internet

https://doi.org/10.1038/s41598-023-41026-3

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