Procrustes is a machine-learning approach that removes cross-platform batch effects from clinical RNA sequencing data

Procrustes is a machine-learning approach that removes cross-platform batch effects from clinical RNA sequencing data

Abstract With the increased use of gene expression profiling for personalized oncology, optimized RNA sequencing (RNA-seq) protocols and algorithms are necessary to provide comparable expression measurements between exome capture (EC)-based and poly-A RNA-seq. Here, we developed and optimized an EC-...

Full description

Bibliographic Details
Main Authors: Nikita Kotlov, Kirill Shaposhnikov, Cagdas Tazearslan, Madison Chasse, Artur Baisangurov, Svetlana Podsvirova, Dawn Fernandez, Mary Abdou, Leznath Kaneunyenye, Kelley Morgan, Ilya Cheremushkin, Pavel Zemskiy, Maxim Chelushkin, Maria Sorokina, Ekaterina Belova, Svetlana Khorkova, Yaroslav Lozinsky, Katerina Nuzhdina, Elena Vasileva, Dmitry Kravchenko, Kushal Suryamohan, Krystle Nomie, John Curran, Nathan Fowler, Alexander Bagaev
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-06020-z

Internet

https://doi.org/10.1038/s42003-024-06020-z

Similar Items