Canagliflozin Alleviates Atherosclerosis Progression through Inflammation, Oxidative Stress, and Autophagy in Western Diet-fed ApoE −/− Mice

Purpose: This study was aimed at investigating the effect of canagliflozin (Cana) on atherosclerosis and further exploring its potential mechanism. Methods: ApoE −/− mice were fed a Western diet (WD) and randomly divided into a WD group and WD+Cana group. After 15 weeks of canagliflozin treatment...

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Bibliographic Details
Main Authors: Qingjuan Zuo, Lili He, Sai Ma, Guorui Zhang, Jianlong Zhai, Zhongli Wang, Tingting Zhang, Yan Wang, Yifang Guo
Format: Article
Language:English
Published: Compuscript Ltd 2024-01-01
Series:Cardiovascular Innovations and Applications
Online Access:https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2023.0093