(-)-Epigallocatechin-3-Gallate Prevents IL-1β-Induced uPAR Expression and Invasiveness via the Suppression of NF-κB and AP-1 in Human Bladder Cancer Cells

(-)-Epigallocatechin-3-Gallate Prevents IL-1β-Induced uPAR Expression and Invasiveness via the Suppression of NF-κB and AP-1 in Human Bladder Cancer Cells

(-)-Epigallocatechin-3-O-gallate (EGCG), a primary green tea polyphenol, has powerful iron scavengers, belongs to the family of flavonoids with antioxidant properties, and can be used to prevent cancer. Urokinase-type plasminogen activator receptors (uPARs) are glycosylphosphatidylinositol (GPI)-anc...

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Bibliographic Details
Main Authors: Dhiraj Kumar Sah, Pham Ngoc Khoi, Shinan Li, Archana Arjunan, Jae-Uk Jeong, Young Do Jung
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
AP-1
cell invasion
EGCG
IL-1β
Urokinase-type plasminogen activator receptor (uPAR)
NF-κB
Online Access:https://www.mdpi.com/1422-0067/23/22/14008

Internet

https://www.mdpi.com/1422-0067/23/22/14008

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