Impact of Allopurinol Pretreatment on Coronary Blood Flow and Revascularization Outcomes after Percutaneous Coronary Intervention in Acute STEMI Patients: A Randomized Double Blind Clinical Trial

INTRODUCTION: The generation of reactive oxygen species, which is induced by the activation of the xanthine oxidase (XO) enzymatic system, is one of the primary causes of ischemia-reperfusion injury for an ischemic heart. Allopurinol, as an XO inhibitor, plays an inhibitory role in free radical prod...

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Bibliographic Details
Main Authors: Mohammad Kermani-Alghoraishi, MD, Hamid Sanei, Kiyan Heshmat-Ghahdarijani, Rahil Ghahramani, Mehrdad Honarvar, Masoumeh Sadeghi
Format: Article
Language:English
Published: Vesnu Publications 2023-11-01
Series:ARYA Atherosclerosis
Subjects:
Online Access:https://arya.mui.ac.ir/article_30948_af4b68a6ccf1d0073b59c970405568be.pdf