PNPLA3—A Potential Therapeutic Target for Personalized Treatment of Chronic Liver Disease

Patatin-like phospholipase domain-containing protein 3 (PNPLA3) is a lipid droplet-associated protein that has been shown to have hydrolase activity toward triglycerides and retinyl esters. The first evidence of PNPLA3 being associated with fatty liver disease was revealed by a genome-wide associati...

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Bibliographic Details
Main Author: Xiaocheng Charlie Dong
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2019.00304/full