Prediction of anti-TNF therapy failure in ulcerative colitis patients by ensemble machine learning: A prospective study

Prediction of anti-TNF therapy failure in ulcerative colitis patients by ensemble machine learning: A prospective study

Nowadays, anti-TNF therapy remarkably improves the medical management of ulcerative colitis (UC), but approximately 40 % of patients do not respond to this treatment. In this study, we used 79 anti-TNF-naive patients with moderate-to-severe UC from four cohorts to discover alternative therapeutic ta...

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Bibliographic Details
Main Authors: Mohammad Hossein Derakhshan Nazari, Shabnam Shahrokh, Leila Ghanbari-Maman, Samaneh Maleknia, Mahsa Ghorbaninejad, Anna Meyfour
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Heliyon
Subjects:
Anti-TNF therapy
Biomarker
Inflammatory bowel disease
Ulcerative colitis
Ensemble machine learning
Inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023083627

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http://www.sciencedirect.com/science/article/pii/S2405844023083627

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