Mitochondrial permeability transition pore as a selective target for anti-cancer therapy

Mitochondrial permeability transition pore as a selective target for anti-cancer therapy

Mitochondrial outer membrane permeabilization (MOMP) is the ultimate step in dozens of lethal apoptotic signal transduction pathways which converge on mitochondria. One of the representative systems proposed to be responsible for the MOMP is the mitochondrial permeability transition pore (MPTP). Alt...

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Bibliographic Details
Main Authors: Dong Hoon eSuh, Mi-Kyung eKim, Hee Seung eKim, Hyun Hoon eChung, Yong Sang eSong
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-03-01
Series:Frontiers in Oncology
Subjects:
Apoptosis
Mitochondria
Cancer
Mitochondrial Permeability Transition Pore
anticancer therapy
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00041/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00041/full

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