A statistical framework for analyzing hypothesized interactions between cells imaged using multispectral microscopy and multiple immunohistochemical markers

A statistical framework for analyzing hypothesized interactions between cells imaged using multispectral microscopy and multiple immunohistochemical markers

Background: Multispectral microscopy and multiple staining can be used to identify cells with distinct immunohistochemical (IHC) characteristics. We present here a method called hypothesized interaction distribution (HID) analysis for characterizing the statistical distribution of pair-wise spatial...

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Bibliographic Details
Main Authors: Chris J Rose, Khimara Naidoo, Vanessa Clay, Kim Linton, John A Radford, Richard J Byers
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Journal of Pathology Informatics
Subjects:
Cellular interactions
follicular lymphoma
image analysis
immunohistochemical staining
multispectral microscopy
Online Access:http://www.jpathinformatics.org/article.asp?issn=2153-3539;year=2013;volume=4;issue=2;spage=4;epage=4;aulast=Rose

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http://www.jpathinformatics.org/article.asp?issn=2153-3539;year=2013;volume=4;issue=2;spage=4;epage=4;aulast=Rose

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