Serology Assays Used in SARS-CoV-2 Seroprevalence Surveys Worldwide: A Systematic Review and Meta-Analysis of Assay Features, Testing Algorithms, and Performance

Serology Assays Used in SARS-CoV-2 Seroprevalence Surveys Worldwide: A Systematic Review and Meta-Analysis of Assay Features, Testing Algorithms, and Performance

Background: Many serological assays to detect SARS-CoV-2 antibodies were developed during the COVID-19 pandemic. Differences in the detection mechanism of SARS-CoV-2 serological assays limited the comparability of seroprevalence estimates for populations being tested. Methods: We conducted a systema...

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Bibliographic Details
Main Authors: Xiaomeng Ma, Zihan Li, Mairead G. Whelan, Dayoung Kim, Christian Cao, Mercedes Yanes-Lane, Tingting Yan, Thomas Jaenisch, May Chu, David A. Clifton, Lorenzo Subissi, Niklas Bobrovitz, Rahul K. Arora
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Vaccines
Subjects:
serological assay
seroprevalence
performance
sensitivity
specificity
evaluation
Online Access:https://www.mdpi.com/2076-393X/10/12/2000

Internet

https://www.mdpi.com/2076-393X/10/12/2000

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