BitterMatch: recommendation systems for matching molecules with bitter taste receptors

BitterMatch: recommendation systems for matching molecules with bitter taste receptors

Abstract Bitterness is an aversive cue elicited by thousands of chemically diverse compounds. Bitter taste may prevent consumption of foods and jeopardize drug compliance. The G protein-coupled receptors for bitter taste, TAS2Rs, have species-dependent number of subtypes and varying expression level...

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Bibliographic Details
Main Authors: Eitan Margulis, Yuli Slavutsky, Tatjana Lang, Maik Behrens, Yuval Benjamini, Masha Y. Niv
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Journal of Cheminformatics
Subjects:
Bitter
GPCRs
Taste
Machine learning
Drugs
Online Access:https://doi.org/10.1186/s13321-022-00612-9

Internet

https://doi.org/10.1186/s13321-022-00612-9

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