Topical Nanoemulsion of a Runt-related Transcription Factor 1 Inhibitor for the Treatment of Pathologic Ocular Angiogenesis

Topical Nanoemulsion of a Runt-related Transcription Factor 1 Inhibitor for the Treatment of Pathologic Ocular Angiogenesis

Purpose: To test the efficacy of runt-related transcription factor 1 (RUNX1) inhibition with topical nanoemulsion containing Ro5-3335 (eNano-Ro5) in experimental ocular neovascularization. Design: Preclinical experimental study. Participants: In vitro primary culture human retinal endothelial cell (...

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Bibliographic Details
Main Authors: Santiago Delgado-Tirado, MD, Lucia Gonzalez-Buendia, MD, Miranda An, BA, Dhanesh Amarnani, MS, Daniela Isaacs-Bernal, BSc, Hannah Whitmore, PhD, Said Arevalo-Alquichire, PhD, David Leyton-Cifuentes, BME, Jose M. Ruiz-Moreno, MD, PhD, Joseph F. Arboleda-Velasquez, MD, PhD, Leo A. Kim, MD, PhD
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Ophthalmology Science
Subjects:
Choroidal neovascularization
Cornea neovascularization
RUNX1
Topical ophthalmic
Treatment
Online Access:http://www.sciencedirect.com/science/article/pii/S2666914522000525

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http://www.sciencedirect.com/science/article/pii/S2666914522000525

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