Oral Insulin Delivery in Diabetic Rats by PLGA Nanoparticles Combined with a Protease Inhibitor (N-Ethylmaleimide)

Oral Insulin Delivery in Diabetic Rats by PLGA Nanoparticles Combined with a Protease Inhibitor (N-Ethylmaleimide)

Nanoparticles have shown a certain potential to overcome the drawbacks of oral peptide delivery in the gastrointestinal tract such as low peptide stability and permeability. Insulin PLGA NP were prepared using a modified double emulsion solvent evaporation technique. Insulin PLGA NP were composed fr...

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Bibliographic Details
Main Authors: Ahmed M Faheem, Dalia Abdeĺkader, Mohamed A. Osman, Paul A. McCarron, Sanaa A. El-Gizawy
Format: Article
Language:English
Published: University of Huddersfield Press 2019-04-01
Series:British Journal of Pharmacy
Subjects:
diabetes mellitus
nanoparticles
human insulin
protease inhibitor
Online Access:https://www.bjpharm.org.uk/article/id/588/

Internet

https://www.bjpharm.org.uk/article/id/588/

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