Age-Related Decline in Gangliosides GM1 and GD1a in Non-CNS Tissues of Normal Mice: Implications for Peripheral Symptoms of Parkinson’s Disease

Age-Related Decline in Gangliosides GM1 and GD1a in Non-CNS Tissues of Normal Mice: Implications for Peripheral Symptoms of Parkinson’s Disease

The purpose of this study was to determine whether the age-related decline in a-series gangliosides (especially GM1), shown to be a factor in the brain-related etiology of Parkinson’s disease (PD), also pertains to the peripheral nervous system (PNS) and aspects of PD unrelated to the central nervou...

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Bibliographic Details
Main Authors: Suman Chowdhury, Gusheng Wu, Zi-Hua Lu, Ranjeet Kumar, Robert Ledeen
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Biomedicines
Subjects:
Parkinson’s disease
GM1 ganglioside
aging
motor impairment
memory impairment
peripheral tissues
Online Access:https://www.mdpi.com/2227-9059/11/1/209

Internet

https://www.mdpi.com/2227-9059/11/1/209

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