AIM2 promotes irradiation resistance, migration ability and PD-L1 expression through STAT1/NF-κB activation in oral squamous cell carcinoma

AIM2 promotes irradiation resistance, migration ability and PD-L1 expression through STAT1/NF-κB activation in oral squamous cell carcinoma

Abstract Background Radioresistance and lymph node metastasis are common phenotypes of refractory oral squamous cell carcinoma (OSCC). As a result, understanding the mechanism for radioresistance and metastatic progression is urgently needed for the precise management of refractory OSCC. Recently, i...

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Bibliographic Details
Main Authors: Hui-Wen Chiu, Hsin-Lun Lee, Hsun-Hua Lee, Hsiao-Wei Lu, Kent Yu-Hsien Lin, Yuan-Feng Lin, Che-Hsuan Lin
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Journal of Translational Medicine
Subjects:
Radioresistance
Metastasis
PD-L1
AIM2
Immune checkpoint inhibitors
Oral squamous cell carcinoma
Online Access:https://doi.org/10.1186/s12967-023-04825-w

Internet

https://doi.org/10.1186/s12967-023-04825-w

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