A novel biomechanical analysis of gait changes in the MPTP mouse model of Parkinson’s disease

Parkinson’s disease (PD) is an age-associated neurodegenerative disorder hallmarked by a loss of mesencephalic dopaminergic neurons. Accurate recapitulation of the PD movement phenotype in animal models of the disease is critical for understanding disease etiology and developing novel therapeutic tr...

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Bibliographic Details
Main Authors: Werner J. Geldenhuys, Tamara L. Guseman, Ilse S. Pienaar, Dean E. Dluzen, Jesse W. Young
Format: Article
Language:English
Published: PeerJ Inc. 2015-08-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/1175.pdf