Early tension regulation coupled to surface myomerger is necessary for the primary fusion of C2C12 myoblasts

Here, we study the time-dependent regulation of fluctuation–tension during myogenesis and the role of the fusogen, myomerger. We measure nanometric height fluctuations of the basal membrane of C2C12 cells after triggering differentiation. Fusion of cells increases fluctuation–tension but prefers a t...

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Bibliographic Details
Main Authors: Madhura Chakraborty, Athul Sivan, Arikta Biswas, Bidisha Sinha
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.976715/full