Early tension regulation coupled to surface myomerger is necessary for the primary fusion of C2C12 myoblasts
Here, we study the time-dependent regulation of fluctuation–tension during myogenesis and the role of the fusogen, myomerger. We measure nanometric height fluctuations of the basal membrane of C2C12 cells after triggering differentiation. Fusion of cells increases fluctuation–tension but prefers a t...
Main Authors: | Madhura Chakraborty, Athul Sivan, Arikta Biswas, Bidisha Sinha |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-10-01
|
Series: | Frontiers in Physiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2022.976715/full |
Similar Items
-
IL-4 Signaling Promotes Myoblast Differentiation and Fusion by Enhancing the Expression of MyoD, Myogenin, and Myomerger
by: Mitsutoshi Kurosaka, et al.
Published: (2023-04-01) -
Expression of Myomaker and Myomerger in myofibers causes muscle pathology
by: Phillip C. Witcher, et al.
Published: (2023-05-01) -
Effect of heterogeneous substrate adhesivity of follower cells on speed and tension profile of leader cells in primary keratocyte collective cell migration
by: Madhura Chakraborty, et al.
Published: (2022-03-01) -
Fer1L5, a Dysferlin Homologue Present in Vesicles and Involved in C2C12 Myoblast Fusion and Membrane Repair
by: R. Usha Kalyani, et al.
Published: (2020-11-01) -
The importance of intermediate filaments in the shape maintenance of myoblast model tissues
by: Irène Nagle, et al.
Published: (2022-12-01)