Next-generation sequencing for pediatric CNS tumors: does it add value in a middle-income country setup?

Next-generation sequencing for pediatric CNS tumors: does it add value in a middle-income country setup?

IntroductionAdvances in molecular diagnostics led to improved targeted interventions in the treatment of pediatric CNS tumors. However, the capacity to test for these is limited in LMICs, and thus their value needs exploration.MethodsWe reviewed our experience with NGS testing (TruSight RNA Pan-Canc...

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Bibliographic Details
Main Authors: Nisreen Amayiri, Maysa Al-Hussaini, Bayan Maraqa, Shaza Alyazjeen, Qasem Alzoubi, Awni Musharbash, Ahmad Kh. Ibrahimi, Nasim Sarhan, Mouness Obeidat, Cynthia Hawkins, Eric Bouffet
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Oncology
Subjects:
next-generation sequencing (NGS)
children
CNS tumors
low-middle-income countries (LMIC)
targeted therapy
compassionate access
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1329024/full

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https://www.frontiersin.org/articles/10.3389/fonc.2024.1329024/full

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